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硼替佐米的相关介绍
硼替佐米(Bortezomib),为黄色固体的化学品,商品名 :万珂® VELCADE®,中文别名:MG-341;硼替佐米杂质;保特佐米,熔点:122-124°C,分子式 :C19H25BN4O4,分子量 :384.23700,用于既往未经治疗的且不适合大剂量化疗和骨髓抑制的多发性骨髓瘤患者的治疗;或单药用于至少接受过一种或一种以上治疗后复发的多发性骨髓瘤患者的治疗;本品可用于复发或难治性套细胞淋巴瘤患者的治疗,此患者在使用本品前至少接受过一种治疗。用于该适应症的安全有效性数据来自国外一项针对既往治疗后复发的套细胞淋巴瘤的单臂Ⅱ期临床研究,尚缺乏针对中国人群的临床研究数据。
硼替佐米杂质有哪些
中文名称 | 英文名称 | CAS号 |
硼替佐米标准品 | Bortezomib | 179324-69-7 |
硼替佐米杂质1 | Bortezomib Amide Analog | 289472-80-6 |
硼替佐米杂质2 | Bortezomib Acid Analog | 114457-94-2 |
硼替佐米杂质3 | Bortezomib (2R)-Acid | 1608986-16-8 |
硼替佐米杂质4 | Desisobutyl-n-butyl Bortezomib | 1104011-35-9 |
硼替佐米杂质5 | (1R, 2R)-Bortezomib | 1132709-15-9 |
硼替佐米杂质6 | (1S, 2S)-Bortezomib | 1132709-14-8 |
硼替佐米杂质7 | (1S, 2R)-Bortezomib | 1132709-16-0 |
硼替佐米杂质8 | PS-619 | |
硼替佐米杂质9 | Bortezomib Hydroxy (1R, 2S)-Isomer,(R)-Hydroxy Des(boric Acid) Bortezomib | 289472-78-2 |
硼替佐米杂质10 | Bortezomib Hydroxy (1R, 2R)-Isomer,(R,R)-Hydroxy Des(boric Acid) Bortezomib | |
硼替佐米杂质11 | Bortezomib Hydroxy (1S, 2S)-Isomer,(R)-Hydroxy Des(boric Acid) Bortezomib | 289472-81-7 |
硼替佐米杂质12 | Bortezomib Acid Methyl Ester | 73058-37-4 |
硼替佐米杂质13 | Bortezomib Pinanediol Impurity,(1R)-(S)-Pinanediol-N-(2-pyrazinylcarbonyl)-L-phenylalanine-L-leucine boronate | 205393-22-2 |
硼替佐米杂质14 | Bortezomib Impurity N,(R)-Hydroperoxy Des(boric Acid) Bortezomib,Bortezomib R-Hydroxyperoxide | 886979-78-8 |
硼替佐米杂质15 | Bortezomib Impurity M,(S)-Hydroperoxy Des(boric Acid) Bortezomib,Bortezomib R-Hydroxyperoxide | 886979-81-3 |
硼替佐米杂质16 | N-((S)-1-(((S)-1-methoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide | |
硼替佐米杂质17 | N-((S)-1-(((S)-1-methoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide | |
硼替佐米杂质18 | (S)-N-(1-(isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide | 1446194-56-4 |
硼替佐米杂质19 | (S,E)-N-(1-((3-methylbut-1-en-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide | |
硼替佐米杂质20 | (S)-N-(1-formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide | |
硼替佐米杂质21 | 3-Hydroxy Bortezomib | |
硼替佐米杂质22 | Bortezomib N-Hexyl Impurity,Desisobutyl-n-pentyl Bortezomib | |
硼替佐米杂质23 | Bortezomib L-Phenylalanyl Analog,L-Phenylalanine-bortezomib | 1194235-41-0 |
硼替佐米杂质24 | Bortezomib D-Phenylalanyl Analog,D-Phenylalanine-bortezomib |